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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 19.7
Human Site: S550 Identified Species: 33.33
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S550 P S Y L D T E S T S G T S S P
Chimpanzee Pan troglodytes XP_531552 2298 258112 S550 P S Y L D T E S T S G T S S P
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S538 P S Y L D T E S T S G T S S P
Dog Lupus familis XP_544874 2297 257913 P550 P S Y L D M E P T S G S M S P
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 P550 P S Y L D L E P S S G N S S P
Rat Rattus norvegicus XP_001055500 2294 257490 E549 P P S Y L D M E P T S G N S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 S550 P A Y L D I E S G S G N T S P
Chicken Gallus gallus XP_001232723 2283 257889 T548 P S Y L D I E T G S R N G S P
Frog Xenopus laevis Q642P2 2270 256829 L546 V Q M P P A F L D M E T P S S
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 N573 S K S D S R L N Q F A E N T L
Honey Bee Apis mellifera XP_395999 2434 273219 T537 E T K L D T I T T T I N D N S
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 L627 R S Q T D A C L S Q C L S A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 S37 R A L E R F D S V T E W A D Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 73.3 13.3 N.A. 66.6 60 13.3 0 N.A. 0 26.6 20 N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 26.6 N.A. 80 66.6 13.3 0 N.A. 20 53.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 15 0 0 0 0 8 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 8 65 8 8 0 8 0 0 0 8 8 0 % D
% Glu: 8 0 0 8 0 0 50 8 0 0 15 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 15 0 43 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 8 0 0 0 8 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 58 8 8 8 15 0 0 0 8 0 0 15 % L
% Met: 0 0 8 0 0 8 8 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 29 15 8 0 % N
% Pro: 58 8 0 8 8 0 0 15 8 0 0 0 8 0 50 % P
% Gln: 0 8 8 0 0 0 0 0 8 8 0 0 0 0 0 % Q
% Arg: 15 0 0 0 8 8 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 50 15 0 8 0 0 36 15 50 8 8 36 65 22 % S
% Thr: 0 8 0 8 0 29 0 15 36 22 0 29 8 8 0 % T
% Val: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 50 8 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _